Niacyna B3 w leczeniu

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W badaniach laboratoryjnych wykazano, iż niacyna w dawkach używanych do obniżania cholesterolu może powodować wady wrodzone u testowanych zwierząt. Opinie lekarzy należałoby wziąć pod uwagę, bowiem długotrwałe przyjmowanie niacyny w dawce 0,5 g może być niebezpieczne. If you take any medicines or supplements regularly, talk to your doctor before you start using niacin supplements. Bardzo wysokie dawki niacyny mogą powodować zmiany w plamce żółtej, pogrubianie plamki żółtej oraz siatkówki, co prowadzi do pogorszenia i w konsekwencji utraty zdolności widzenia. Prescription niacin might benefit people with high cholesterol who aren't able to take statins or haven't been able to control their cholesterol levels through use of a statin, diet and exercise.

Despite the proven lipid changes, niacin has not been found useful for decreasing the risk of cardiovascular disease in those already on a statin.As a cholesterol treatment, there are good studies showing that niacin can boost levels of good HDL cholesterol and lower triglycerides.

A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions.Kiedy biologiczne znaczenie kwasu nikotynowego zostało odkryte, postanowiono zmienić nazwę kwasu nikotynowego.

The long-term use of niacin at greater than or equal to 2grams per day also significantly increases the risk of cerebral hemorrhage, ischemic stroke, gastrointestinal ulceration and bleeding, diabetes, dyspepsia, and diarrhea. Niacin occurs naturally in many foods, including greens, meat, poultry, fish, and eggs, although in a fraction of the dose shown to achieve changes in cholesterol.When given as a treatment for people with high cholesterol, niacin supplements can cause flushing, which is a feeling of warmth, redness, itching or tingling of the face, neck, arms or upper chest. However, if needed to prevent or treat niacin deficiency, niacin is likely safe to take during pregnancy and in breast-feeding women when used in recommended amounts. For this reason, people who consume corn as tortillas or hominy are at less risk of niacin deficiency. Niacinamide may be helpful for severe acne, especially inflammatory forms like papules and pustules. It also tends to occur in less developed areas where people eat maize (corn) as a staple food, as maize is the only grain low in digestible niacin.

Metaanaliza 11 kontrolowanych badań klinicznych przeprowadzona w 2009 roku wykazała, iż niacyna, użyta jako jedyny lek lub też w kombinacji z innymi lekami, znacznie zmniejszyła ilość głównych incydentow chorób wieńcowych (zawałów, udarów mózgu) oraz rozwój miażdżycy [30].Prescription niacin is used to increase high-density lipoprotein (HDL) cholesterol — the "good" cholesterol that helps remove low-density lipoprotein (LDL), the "bad" cholesterol, from your bloodstream. Pellagra is a consequence of a corn-dominant diet because the niacin in corn is poorly bioavailable and corn proteins are low in tryptophan compared to wheat and rice proteins. To problem, bo niewystarczający jej poziom generuje kłopoty zdrowotne — witamina D wpływa bowiem na funkcjonowanie niemal. However, if you are deficient or have another condition that may benefit from higher doses, your doctor may recommend a supplement.